Kodi Urolithin A angakhale njira yothetsera vutolo kuti akhalebe wathanzi?

● Bioactivity ndi mphamvu ya urolixin A

1:Anti-kukalamba zotsatira

Limbikitsani ntchito ya mitochondrial: urolithin A ikhoza kulimbikitsa mitophagy, kuthandizira kuchotsa mitochondria yowonongeka, kulimbikitsa mbadwo wa mitochondria yatsopano, yogwira ntchito, kuti ikhalebe ndi mphamvu ya metabolism ya maselo ndi kuchepetsa kukalamba.

2:Mphamvu ya neuroprotective

Chepetsani neuroinflammation: Urolitin A imatha kuwoloka chotchinga chamagazi-muubongo, kuchepetsa amyloid beta (Aβ) ndi zotupa za protein ya tau, komanso kuyambitsa mitochondrial autophagy, potero kumapangitsanso zizindikiro za matenda a neurodegenerative monga matenda a Alzheimer's ndi Parkinson's.

3:Chitetezo cha minofu

Kuonjezera mphamvu ya minofu ndi kupirira: Urolixin A akhoza kupititsa patsogolo thanzi la minofu, kuwonjezera mphamvu za minofu ndi kupirira, ndipo ali ndi gawo lothandizira pa matenda okhudzana ndi matenda a minofu.

4:Anti-kutupa kwenikweni

Kuletsa zinthu zowononga: urolithin A ikhoza kulepheretsa kupanga ndi kutulutsa zinthu zowonongeka monga IL-6 ndi TNF-α, ndi kuchepetsa kuyankhidwa kwa kutupa.Kuwongolera njira zowonetsera zotupa: Mwa kulepheretsa kuyambitsa kwa NF-κB, MAPK ndi njira zina zowonetsera zotupa, urolitin A amachepetsanso kuyankha kotupa.

5:antioxidation

Kusakaza ma radicals aulere: Urolixin A amatha kuchotsa mwachindunji ma radicals aulere ndikuchepetsa kuwonongeka kwa oxidative kupsinjika pama cell.Kupititsa patsogolo chitetezo cha antioxidant: Urolixin A imatha kupititsa patsogolo mphamvu yoteteza antioxidant ya maselo poyambitsa njira ya Nrf2 antioxidant ndikuwongolera mafotokozedwe amitundu yosiyanasiyana ya antioxidant monga glutathione peroximudase.

6:Mphamvu ya Antitumor

Kuletsa kuchulukana kwa maselo otupa: urolixin A ingalepheretse kufalikira, kuwukira ndi kufalikira kwa khansa ya prostate, khansa ya m'matumbo ndi ma cell ena otupa.

7:Kupititsa patsogolo matenda a metabolic

Kuwongolera shuga m'magazi ndi lipids m'magazi: urolithin A imatha kuwongolera njira ya kagayidwe kachakudya m'thupi ndipo imathandizira kuwongolera shuga m'magazi ndi lipids.Anti-obesity: Poyambitsa kuyambitsa mafuta a bulauni ndi mafuta oyera a Browning, urolixin A imatha kufulumizitsa catabolism yamafuta ndikuletsa kudzikundikira kwamafuta chifukwa cha zakudya.

8:Kupititsa patsogolo matenda a impso

Kuchepetsa kuvulala kwa impso: Urolixin A ikhoza kuchepetsa kuvulala kwa impso mwa kuyambitsa mitochondrial autophagy ya maselo a impso, kuchepetsa kusonkhanitsa kwa collagen, kuchepetsa kuchuluka kwa fibrocyte kapena kuchepetsa kuyika kwa minofu ya fiber kuti muchepetse kukula kwa fibrosis.

● Chiyembekezo chogwiritsa ntchito urolithin A

1:Kafukufuku ndi chitukuko cha mankhwala

Urolixin A ndi chandamale chodziwika bwino cha anti-kukalamba, neuroprotective, anti-tumor mankhwala chitukuko chifukwa cha ntchito zake zosiyanasiyana zamoyo.Pakali pano, Mabungwe angapo ofufuza ndi mabizinesi ayamba kuphunzira za chitukuko cha mankhwala a urolixin A, akuyembekeza kupanga mankhwala othandiza komanso otetezeka.

2:Kafukufuku wa zodzoladzola ndi chitukuko

Mphamvu ya antioxidant ndi yotsutsa-kutupa ya urolixin A imapangitsa kuti ikhale ndi mwayi wogwiritsa ntchito zodzoladzola. Powonjezera urolixin A, zodzoladzola zimatha kupititsa patsogolo kukalamba komanso kusintha khungu.

3:Kafukufuku wa chakudya ndi chitukuko

Urolixin A imatha kugwiritsidwa ntchito pazakudya chifukwa cha ntchito zake zosiyanasiyana zamoyo. Mwa kuwonjezera zakudya zokhala ndi ellagitannin kapena urolithin A zowonjezera, zakudya zimatha kuwonjezera mapindu azaumoyo ndikukwaniritsa zosowa za ogula pazakudya zopatsa thanzi.

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